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This mitochondrial respiratory enhancement under oxidative stress conditions is proposed as a primary mechanism of DSIPs stress-protective and neuroprotective potency and connects DSIP biology to the broader field of mitochondria-targeted neuropeptide research

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A 6-weeks intervention trial using daily supplement with -3 PUFA and vitamin D in 56 couples undergoing IVF or ICSI showed no difference in the second cell cycle (CC2) but faster fourth cell cycle (CC4) and a significantly shorted third cell cycle (S3) improving embryo quality (48)

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